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Ozempic is administered as a once-weekly subcutaneous injection , typically starting at a low dose (0.25 mg for 4 weeks) and gradually increasing to therapeutic doses of 0.5 mg, 1 mg, or 2 mg, depending on individual response and tolerability

Patients who experience persistent or severe discomfort should seek professional medical evaluation to determine the best course of care

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The tail suspension test (a measure of behavioural despair) was carried out according to the method described by Steru et al [49], Myniec and Nowak[50], and Onaolapo et al [51]