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Description

Barchetta, I., Cimini, F

5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small molecule that inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that becomes overactive in metabolically aging tissue

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[18] [19] Their detoxification involves both broad-spectrum and specialized enzymatic systems, including families that act on reactive carbonyls and other electrophiles, as well as dedicated pathways for particularly toxic intermediates