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Table 5 Comparison of mortality of bullfrogs in NC, FI and GSH groups after 20 days

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This review article aims at discussing the potential of therapeutic GLP-1 receptor agonists in alleviating depressive symptoms in the context of modern theories surrounding the pathogenesis of this disease and explores their influence on cognitive processes, neurotransmission, modulation of neuroinflammatory processes, effects on HPA axis activity, brain energy balance, and the functioning of the gut-brain axis