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To find relevance to HD, the group used striatal tissues from the SPRDtgHD rat model, which is known to show biphasic changes in dopamine, with early increases followed by later decreases
The nonabsorbable disaccharides were mainly associated with nonsevere gastrointestinal adverse events
Pregnant patients exposed to ZEPBOUND and healthcare providers are encouraged to contact Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979)
These reassuring results can probably be extrapolated to other drugs from all BCS classes
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