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In states of negative energy balance (fasting, BW/FM loss, caloric restriction, hypoglycemia), AgRP neurons are activated leading to increased hunger, increased food seeking and ingestion, and decreased input from eating-inhibitory mechanisms
Many individuals notice: More significant weight loss Improved body composition Better physical endurance Greater motivation to stay consistent This is often when family members and friends begin noticing visible changes
Semaglutide works by making you feel fuller and less hungry, reducing food cravings
Additionally, set up reminder systemssuch as smartphone alarms, calendar notifications, or linking your injection to a specific weekly routineto help prevent future missed doses and maintain treatment consistency
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