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Beyond Month 6: Maintenance Most patients continue at 2.4 milligrams weekly through month 12, when full clinical trial endpoints are typically reached
Track three milestones: smoother texture by week 4, lighter sun spots by week 8, more even overall tone by week 12
Regarding prescribing: under the Human Medicines Regulations 2012 (regulation 167), doctors and some independent prescribers may prescribe unlicensed medicines (known as 'specials') when clinically necessary and when no licensed alternative is suitable, taking personal responsibility for that decision (GMC: Good practice in prescribing and managing medicines and devices)
Discussion and perspectives This review highlights the intricate interplay between the liver and AD through the liver-brain axis, emphasizing its role in metabolic regulation, inflammatory signaling, and cognitive health
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