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The effect of the cone tilting angle is shown in Fig

Another potential regulator of the chronic GSH adaptive response to CS exposure are the glutathione-S-transferases (GSTs) that conjugate GSH to xenobiotics for transport that could stimulate an increase in GSH synthesis to match GSH transport

To further strengthen the directionality of the integrative signal, we performed an additional enrichment analysis restricted to genes showing promoter-associated hypomethylation together with increased expression in RNA-seq