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Figure 3 In another study comparing the neuroprotective effects of two other novel GLP-1/GIP dual receptor agonists (DA-JC4, DA-CH5) with the GLP-1 single receptor agonist liraglutide and the first-generation GLP-1/GIP dual receptor agonist DA-JC1 in MPTP-induced PD mice, the results concluded that the new dual receptor agonists have clear neuroprotective effects (112)
Hyperpigmentation is another common driver, especially in deeper skin tones
They are approved only for type 2 diabetes and obesity management, and clinical evidence for IBD treatment remains extremely limited with no completed randomized controlled trials
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