Unfortunately, unlike roGFPs measuring the redox potentials of GSH/GSSH, peroxynitrite and GSH are not a redox pair and the biological meaning of the ratio of these two species is elusive
Does GHK-Cu work for acne scars
Mechanistically, GHK-Cu appears to act through several pathways: Collagen and elastin remodeling: Gene array work by Finkley et al., reported in the second edition of Cosmeceuticals and Active Cosmetics (Taylor and Francis, 2005), examined GHK-Cu effects on human fibroblast cultures across a nanomolar to low micromolar concentration range and found upregulation of decorin, collagen, and elastin-associated genes
Lipid peroxidation preferentially accumulates at lysosomal membranes and precedes lysosome rupture, transcription factor EB (TFEB) activation, and cathepsin-dependent plasma membrane breakdown, thereby positioning lysosomal stress at the center of population-scale death amplification