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As shown in Table 4 , miRNA levels change various intracellular pathways, and the most prominent implicated pathways are those of NF-B (192, 198, 207, 212, 213, 222, 229, 230, 238), PI3K/Akt (194, 199, 203, 236), JAK/STAT (218, 219), TLR (208, 220), -catenin (215, 217, 235), and Wnt (223, 235)

The measurement of plasma MDA and GSH levels was done at the Biochemistry and Molecular Biology laboratories, Faculty of Medicine, Sriwijaya University using Sigma-Aldrich MDA and GSH assay kits