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alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells Richard J Elliott 1 , Marika Szabo, Mark J Wagner, E Helen Kemp, Sheila MacNeil, John W Haycock Use of low-dose naltrexone in the management of chronic pain conditions: A systematic review Elizabeth Hatfield, Kristine Phillips, Sahar Swidan, Lawrence Ashman PMID: 33228882 DOI: 10.1016/j.adaj.2020.08.019 Sr Care Pharm 2019 Jan 1;34(1):43-46
We suggest instead staggering their application, so using vitamin C in the morning, where it can help with UV protection and antioxidant support, and then using copper peptides at night, where it can work with the skin organ's natural circadian rhythm for repair