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Indeed, it was demonstrated that heterodimerization of 1-cysPrx with GSH-saturated GSTP results in S -glutathionylation of the oxidized cysteine in 1-cysPrx followed by subsequent spontaneous reduction of the mixed disulfide and restoration of enzymatic activity (Manevich et al., 2004)
This is why two people with the same weight and the same C-section can look very different afterwards
When you combine them, you get a powerful synergistic effect
Physiol Rev 56(4):778826 Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D et al (2008) DrugBank: a knowledgebase for drugs, drug actions and drug targets
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