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Most patients microdose with syringes because prefilled injections are not available in the form of microdoses

Accordingly, people with type 2 diabetes, cardiovascular disease, heart failure, or chronic kidney disease should be treated appropriately with an SGLT-2 inhibitor or GLP-1RA, even because more adults with type 2 diabetes in the US have suboptimal glycemic control now compared to 10 years ago, associated with a resurgence in vascular diabetic complications [32]

Gradual tapering or cycling: reduce reliance on interventions as the body heals and incorporate long-term maintenance strategies such as strength training and tailored nutrition