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overweight) and at least one weight-related health condition, such as diabetes, high cholesterol, or high blood pressure
From a pharmacokinetic perspective, semaglutide is administered subcutaneously once weekly and is primarily degraded by proteolytic enzymes rather than being metabolised by the liver's cytochrome P450 enzyme system
Liquid (reconstituted) tirzepatide: Once tirzepatide is in solution, all the degradation pathways discussed earlier become active
June 2023 Update: The American Society of Anesthesiologists (ASA) recommended that users temporarily discontinue Ozempic, Wegovy before elective surgery due to the risk of experiencing nausea and vomiting that could cause suffocation during anesthesia procedures
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