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If a patient is deemed high-risk, it is safer to prescribe the medication cautiously only after fully explaining the potential risks, such as depression or suicidal ideation, to the patient or caregiver and obtaining consent for continuous monitoring
Both compounds are available through research supply channels
Observational studies have produced inconsistent findings, and there is a notable absence of large-scale randomized controlled trials to validate the efficacy of lowering uric acid levels
Phosphoinositide 3-kinase (PI3K) protein expression was significantly increased in the Lira group compared to the model group [54]
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