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Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (82103369) and the China Postdoctoral Science Foundation (2022M710757)

doi: 10.1016/j.mce.2020.111085 21 MaQBealJRBhurkeAKannanAYuJTaylorRNet al

In clinical treatment, the drugs currently undergoing clinical trials are mainly iron chelating agents and antioxidants, detailed in Table 2

There are some lab markers that may be helpful in addressing MCAS: DAO enzymes this is an enzyme that breaks down histamine, so checking for deficiencies can be helpful