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Moreover, studies have shown that GLP-1RA could regulate glucose homeostasis in an insulin-independent mechanism via the 5-AMP-activated protein kinase (AMPK) pathway (36, 37)
doi: 10.1016/j.fct.2025.115603 5 Pal SinghMPal KhaketTBajpaiVKAlfarrajSKimS-GChenLet al
Because retatrutide has not yet been approved for general use, it is not currently possible to definitively state who will or will not be eligible for this treatment in a clinical setting
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