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A 2012 systematic review and meta-analysis by Rossignol and Frye in Molecular Psychiatry found mitochondrial dysfunction in a meaningful subset of children with autism, well above general population rates [9]
These trials showed significant improvements in HF-related symptoms, physical limitations, exercise capacity, and reductions in NT-proBNP, a marker of cardiac stress
Data Synthesis Data were extracted and synthesised in summary tales and figures according to relevant themes including efficacy outcomes and safety outcomes
[19] Clinical trials are reporting weight loss of 20 to 40 lbs per year of use
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