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Cobalamin has a well-documented role in appetite pathway activation

Proton pump inhibitors (PPIs) and H2-receptor antagonists, used for acid reflux, reduce stomach acid production, which can impair dietary B12 absorption, though this does not directly affect injections

Safety check The right choice can change based on history, medication interactions, side effects, budget, and availability

Adding to doctors' worries are concerns about purity and dosing, because users typically buy from websites selling unregulated Chinese product some of which comes from plants that previously produced the deadly opioid fentanyl