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Description

Consistent with this finding, we observed less respiration in response to CI and III substrates in isolated gWAT mitochondria and primary adipocytes from mice lacking adipocyte Ndufs2 (Extended Data Fig

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Nrf2 Structure and Molecular Pathway Nuclear factor-erythroid 2 (NF-E2) related factor 2 (Nrf2), which belongs to the capncollar (CNC)-basic region/leucine zipper (bZIP) transcription factor family, is critical in cytoprotection by inducing expression of antioxidant and detoxifying enzymes and proteins via its binding to the cis-acting antioxidant response element (ARE)

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Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation

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