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These comprehensive effects distinguish GLP-1 pathway support from traditional weight loss approaches that typically focus on single mechanisms such as appetite suppression or metabolism boosting
Notably, WM-CR mice exhibited identical tumor onset and similar progression to SEMA, which supports that weight loss alone may be beneficial independent of GLP1R agonism
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However, GEP44 has a superior therapeutic window, as rats could be treated with higher doses (up to 100 nmol/Kg/d) with no notable adverse effects
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