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In addition to systemic benefits, as early as 1940, it was observed that riboflavin could also have local benefits: vaginal administration of riboflavin in ten women via a lactose tablet was shown to result in an increased acidity and a favorable impact on vaginal bacteria through increased growth of acid-forming bacilli and decrease of pathogens 78

The trial will eventually expand to include more women and participants, but McDonald said the timeline for all of that depends on securing enough funding to launch the project

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