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Tesamorelin is a 44-amino-acid synthetic analog of growth hormone-releasing hormone (GHRH), formed by adding a trans-3-hexenoic acid group to the native GHRH(1-44) sequence

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Attempts to mimic this altered meal processing, such as proximal blockage of nutrient absorption resulting in increased delivery of nutrients in the distal intestine, have shown some promising results in healthy and diabetic humans (403)