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Across GLP-1 and incretin-based therapies, we are seeing outcomes beyond the scale: - fewer major cardiovascular events - kidney protection - improvements in conditions tightly linked to cardiometabolic dysfunction, including sleep apnea biology We should stop treating obesity as a cosmetic problem and start treating it like the systemic disease driver it is, across joints, heart, kidneys, and sleep

For example, NADPH is the electron donor for the enzymatic regeneration of the reduced form of the important antioxidant glutathione (GSH), enabling it to neutralize toxic reactive oxygen species (ROS) that accumulate due to normal and pathological cellular processes

Matalka KZ, Al-Rawashdeh B, et al

Deze route zal deels plaatsvinden, echter het is aantoonbaar van minder belang dan het directe GSH-absorptieproces