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A recent study has shown that the influenza virus matrix 1 protein can induce the production of proinflammatory cytokines and cellular ROS as well as trigger cell death through the activation of TLR4 signaling 28

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Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia

UA also induced an increase in Nrf2, a transcription factor that regulates genes involved in antioxidant response 35