Following the discovery of exendin-4, pharmaceutical companies recognised the therapeutic potential and began developing synthetic versions of this peptide for human use
Obesity leads to chronic inflammation, he said, and that inflammation has very clear effects on your arteries and your cardiovascular system. Reducing that inflammation with GLP-1s, it turns out, reduces cardiovascular risk
Its weight-loss effects are primarily achieved through several mechanisms, including central appetite regulation via hypothalamic pathways enhancing satiety, delayed gastric emptying that prolongs postprandial fullness, improvement of insulin sensitivity and metabolic homeostasis, and reduction of visceral and hepatic fat depots, which may alleviate respiratory mechanical burden and metabolic stress in OSAS (34)
FDA Rolls Back Some Requirements for Isotretinoin-Containing Treatments for Acne The FDA announced that, with approval from a clinician, patients of reproductive age who are prescribed isotretinoin-containing treatments for acne may complete pregnancy testing at home or in other nonmedical settings during or after treatment