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Within the ER, hexose-6-phosphate dehydrogenase converts glucose-6-phosphate and NADP + to 6-phosphogluconate and NADPH in a single step, whereas this process in the cytosol requires two separate enzymes (G6PD and PGLS)
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People with compromised immune systems : Conditions like HIV, cancer treatments, or other immune system disorders can result in reduced glutathione levels, impacting the bodys ability to fight infections and heal
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