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Description

BBB is a biological and physical barrier consisting of astrocytes, pericytes, and brain microvascular endothelial cells (BMECs) that maintains the dynamic between the peripheral circulation and the central nervous system (21)

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5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT) an enzyme linked to metabolic rate regulation, fat storage, and cellular energy balance

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