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Each dose increase during the titration phase can trigger a fresh round of GI symptoms, and diarrhea tends to peak during these escalation steps

Sleep optimization, nutritional support (adequate protein, vitamin C for collagen synthesis, omega-3 fatty acids for inflammation modulation), stress management, and appropriate training load progression all contribute to tissue health

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In summary, these data reiterate that at least some of the glycaemic benefit of GLP-1GIPLani is body weight-independent and is not observed with GLP-1RGIPR co-agonism, even after correction for body weight