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In addition to this, many people have problems metabolizing B12 in low-quality forms like cyanocobalamin due to defects in the MTHFR gene (1) (as many as 40% of people have THIS problem!)

Bora J, Syiem D, Bhan S (2019) Quantitative analysis of total phenolic, flavonoid contents and HPTLC fingerprinting of flower extracts of Phlogacanthus thyrsiflorus Nees

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Proteins were separated by sodium dodecyl sulfate polyacrylamide gel electrophoresis and transferred to polyvinylidene difluoride membranes (Millipore, Bedford, MA, USA)