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[39] What this means is that, disruptions that occur to the gut (for instance, from taking an antibiotic, taking acid-suppressing medications for acid reflux , or eating an inflammatory food like gluten ), can upset the microbiome, cause intestinal permeability ( leaky gut ), and result in a shared gut-brain inflammatory event
A systematic review of 76 different clinical trials looking at the risk of gallbladder disease for people taking GLP-1 agonists showed that there was an increase in risk for the development of gallbladder disease when taken at higher doses for long periods of time
and decreasing the expression of dynamin-related protein 1 (Drp1) and mitochondrial fission protein 1 (Fis1) [17]
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