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Isopropyl -d-1-thiogalactopyranoside (IPTG) was added to a final concentration of 1 mM and the culture was further incubated at 18 C overnight

More importantly, comparable levels are maintained for at least 4 months that suggests these adaptive responses are established early and can be maintained for extended periods of time

Microglia are initially activated to stage 1 DAM, which are characterized by a downregulation of homeostatic microglial genes including p2ry12 and cx3cr1 , and an upregulation of genes including trem2 , tyrobp and apoe

Safety, Compliance, and Research Protocols This product is strictly for laboratory research use only and is not FDA-approved for human consumption