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Med Hypotheses 2005
S.GerdesV
3.5 Impact on Cardiovascular Risk Factors It improves lipid profiles, reduces body weight, and lowers blood pressure
2 The immunotherapeutic landscape of osteosarcoma: challenges and resistance mechanisms 2.1 The immunosuppressive TME The osteosarcoma TME is a complex ecosystem comprising malignant cells, stromal cells, immune infiltrates, and ECM components embedded within a mineralized bone scaffold ( TAMs represent the most abundant immune cell population within the osteosarcoma TME, often accounting for over 50% of infiltrating immune cells ( MDSCs constitute another major immunosuppressive population in the osteosarcoma TME
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