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15 GSSG is unable to perform antioxidant functions but can be converted back to rGSH by glutathione reductase (GSR), 15,17,18 which requires the oxidation of NADPH to NADP+

: , L-carnitine , , - : L-carnitine

c , Relative acetyl-CoA abundance in ER isolated from Slc33a1 -knockout KPK cells expressing wild-type SLC33A1 , 2YA SLC33A1 variants, or vector control

Commonly reported side effects include: nausea diarrhea constipation abdominal discomfort mild reactions at the injection site (for injectable forms) These effects are usually temporary and tend to improve over time , especially when treatment is started with lower doses that are gradually increased