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Working with mouse models, a research team from Michigan State University concluded that reducing levels of the antioxidant glutathione (GSH) may help to protect the colon from inflammatory induced damage from colitis

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A subset of dedifferentiated -cells were at early stage to convert into -cell in LOsG-treated animals As a subset of FoxO1-deficient -cells adapts the -cell fate, resulting in hyperglucagonemia 22 , we determined pancreatic glucagon mRNA in LOsG-treated -cells, which were associated with low or absent FoxO1 expression