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People with chronic kidney disease (CKD) should not increase protein intake without specialist advice, as higher intakes may be contraindicated

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However, in individuals with type 2 diabetes, infusions of GIP(3-30)NH 2 reduced glucagon concentrations (78), illustrating the potential of GIP receptor antagonism to limit the paradoxical postprandial hyperglucagonemia in individuals with type 2 diabetes (93)