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"A 1-year multicenter placebo-controlled study of ALCAR in Alzheimer's disease." Neurology 1996;47(3):705-11
10.1258/ebm.2011.011152 Exp
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While some receptor adaptation does occur (explaining why gastric emptying effects attenuate over time even as doses increase), the central appetite-suppressing effects appear to be maintained through mechanisms that do not rely solely on gastric motility
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