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When you eat a meal, your intestinal L-cells release GLP-1, which signals the pancreas to produce insulin, tells the liver to reduce glucose output, and communicates with the brain to register satiety

For instance, in October 2024, Novo Nordisk made significant strides with Rybelsus, as the company announced its plan to expand the drugs indication to prevent major adverse cardiovascular events (MACE) in patients with Type 2 diabetes, cardiovascular disease (CVD), or chronic kidney disease (CKD)

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However, since digestive side effects are more common at higher doses, the reduced level of Ozempic in your body means these side effects may also ease