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In both trial programs, initial dose escalation of semaglutide was implemented to mitigate gastrointestinal adverse events
[1] [2] Tirzepatide (Mounjaro, Zepbound) is a related but distinct dual GIP/GLP-1 receptor agonist
In some cases, people who did this ended up in urgent care with dehydration so severe they needed IV fluids
The half-life of tirzepatide in the bloodstream was approximately 5 days
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