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Polyurea dendrimer folate-targeted nanodelivery of L-buthionine sulfoximine as a tool to tackle ovarian cancer chemoresistance

TABLE 1 Characteristics of patients with AAV at diagnosis (N = 71)

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The ROS scavenging property of Sp was also replicated in the Drosophila models knocked-down for essential antioxidant enzymes catalase and glutathione peroxidase, where neuronal cells of 15 days AEL flies genetically expressing a redox biosensor, roGFP showed reduced fluorescence under Sp treatment (Fig