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At this years conference, organizations across healthcare, including behavioral coaching and well-being, discussed new initiatives to address challenges with GLP-1 access and long-term behavioral change
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Metformin, the current first-line treatment in T2DM, has an unclear antidepressant effect [166] despite identified direct mechanisms and pleiotropic effects, including inhibition of angiotensin II and NF-B factor, normalization of gut microbiota, and intestinal permeabilization, and in vivo experimental data [167] supporting its potential benefits
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