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The SURPASS-1 trial demonstrated significant improvements in glycemic control and substantial reductions in body weight with all three doses of tirzepatide (5 mg, 10 mg, or 15 mg) compared to placebo over a 40-week period
Case reports point to a benefit for its use in thyroid storm when combined with methimazole, and an early trial found that a dose of at least 2 g per day could reverse and prevent symptoms of intentionally induced hyperthyroidism among women given a fixed TSH-suppressive dose
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These serious side effects can occur with Ozempic
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