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doi: 10.1055/s-0042-109065 Summary Keywords diabetes mellitus type 2, cardiovascular disease, cardiovascular risk, diabetic kidney disease, sodium-glucose cotransporter-2 inhibitor, glucagon-like peptide-1 receptor agonist, aldosterone, renin Citation Puglisi S, Rossini A, Poli R, Dughera F, Pia A, Terzolo M and Reimondo G (2021) Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists on Renin-Angiotensin-Aldosterone System
Titrate over 16-20 weeks: Lifestyle Synergy GLP-1s amplify diet/exercise: Aim 500kcal deficit, 150min moderate activity weekly
Dietary fibre intake is a cornerstone of constipation management
Treatment typically begins at a low dose with incremental increases every 4 weeks until reaching the maintenance dose or the maximum tolerated dose
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