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A lack of vitamin B12 can often lead to fatigue and weakness due to megaloblastic anemia a blood disorder that causes unusually large red blood cells (megaloblasts) and a lower red blood cell count, which results in a lower supply of oxygen to the body

Although SGLT2 inhibitors are proven to block the SREBP1c - ACC axis in metabolic tissues of animal models, we still need further proof to know if they directly affect tubular ferroptosis by regulating DNL in DKD (Kim et al., 2019)

(1) Neural Network Enhancement: Improved synaptic formation and plasticity lead to stronger and more efficient neural networks, which are vital for cognitive processes and neural health

Ultimately, the radical chain reactions will be blocked by the antioxidant enzymes superoxide dismutase (SOD) in association with catalase or GPX that determines the complete free radicals scavenging (Winterbourn, 1993)