Berk M, Williams LJ, Jacka FN, ONeil A, Pasco JA, Moylan S, et al
If any apply, the medication should not be prescribed: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Known serious hypersensitivity to the active medication or to a related incretin-receptor agonist Clinical precautions that prompt careful screening These are not absolute contraindications on the FDA label, but they meaningfully change the risk-benefit conversation
Learn more: Tirzepatide dosage: Finding the right dose for weight loss Side effects are disrupting normal eating patterns Side effects like nausea, constipation, diarrhea, and stomach pain are common with tirzepatide and tend to show up in the first few weeks or after dose increases
Generally, you may be a good candidate for GLP-1 therapy if: You have a body mass index (BMI) that falls within a certain range, typically 27 or higher with a weight-related health condition, or 30 or higher without one