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Full results typically appear after a few months of consistent use
SREBP-2 inhibition by small interfering RNA in GLP-1RAs treated cells amplified the reduction in the expression of HMGCR , SQLE , LXR , CYP7A1 , and PCSK9 genes and HMGCR protein, as well as the increase in expression of the LDLR gene
To adjust for potential confounding, we used inverse probability of treatment weighting (IPTW) based on propensity scores, a method that allows balancing without losing generalisability [17]
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