Why Undergo Medical Weight Loss
David Perlmutter 45:57 Thank you
Possible reasons include Type 1 diabetes diagnosis, advanced Type 2 diabetes with severely depleted beta cells, contraindication to GLP-1 drugs (thyroid cancer history, pancreatitis history), insurance or cost barriers, prior GLP-1 intolerance, or very high blood sugar requiring immediate insulin coverage
Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility