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The medications, also known as GLP-1 drugs, also reduce glucagon, a hormone secreted by the liver that causes glucose levels to rise in the bloodstream
No controlled trial has evaluated the combination
The offer followed shortly after Metsera struck a deal to sell itself to Novos rival, Pfizer, that was worth up to $7.3 billion (which Metsera can still get out of)
Treating hypothyroidism before starting a GLP-1 improves weight loss outcomes, insulin sensitivity, and minimizes side effects
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