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Examples of drugs that can raise the risk of serotonin syndrome if taken with Vyvanse include: selective serotonin reuptake inhibitor (SSRI) antidepressants, such as: paroxetine (Paxil, Pexeva) sertraline (Zoloft) escitalopram (Lexapro) fluoxetine (Prozac) serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants, such as: lithium (Lithobid), a drug for bipolar disorder and depression buspirone, a drug for anxiety triptan medications for migraine, such as: almotriptan (Axert) eletriptan (Relpax) frovatriptan (Frova) naratriptan (Amerge) rizatriptan (Maxalt) sumatriptan (Imitrex) zolmitriptan (Zomig) certain pain medications, such as: other amphetamine drugs, such as: amphetamine (Evekeo, Adzenys, Dynavel) amphetamine/dextroamphetamine (Adderall, Mydayis) dextroamphetamine (Dexedrine) methamphetamine (Desoxyn) monoamine oxidase inhibitors (MAOIs), such as: phenelzine (Nardil) isocarboxazid (Marplan) If you take any of these drugs, talk with your doctor before taking Vyvanse

This includes dietary modification, physical activity programmes tailored to their functional capacity, and behavioural interventions