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To establish bioequivalence, the C max, 024h,SS estimated treatment ratio was required to be fully contained within 0.80001.2500 and the 90% CI of the C max, 024h,SS estimated treatment ratio fully contained within 0.69841.4319 for group 1, 0.72731.3749 for group 2 and 0.73281.3646 for group 3, and the 90% CI of the AUC 024h,SS treatment ratio was required to be fully contained within 0.80001.2500
These findings suggest oral administration can be effective, at least in rodent models
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